abstract：: ...

journal_title：Nature

authors： Witze A

更新日期：2019-01-01 00:00:00

abstract：: ...

journal_title：Nature

authors： Beekes M,Mielke M,Thomzig A

更新日期：2019-01-01 00:00:00

abstract：:Diffuse gliomas are the most common malignant brain tumours in adults and include glioblastomas and World Health Organization (WHO) grade II and grade III tumours (sometimes referred to as lower-grade gliomas). Genetic tumour profiling is used to classify disease and guide therapy1,2, but involves brain surgery for ti...

journal_title：Nature

authors： Miller AM,Shah RH,Pentsova EI,Pourmaleki M,Briggs S,Distefano N,Zheng Y,Skakodub A,Mehta SA,Campos C,Hsieh WY,Selcuklu SD,Ling L,Meng F,Jing X,Samoila A,Bale TA,Tsui DWY,Grommes C,Viale A,Souweidane MM,Tabar V,

更新日期：2019-01-01 00:00:00

abstract：:Increasing human populations around the global coastline have caused extensive loss, degradation and fragmentation of coastal ecosystems, threatening the delivery of important ecosystem services1. As a result, alarming losses of mangrove, coral reef, seagrass, kelp forest and coastal marsh ecosystems have occurred1-6....

journal_title：Nature

authors： Murray NJ,Phinn SR,DeWitt M,Ferrari R,Johnston R,Lyons MB,Clinton N,Thau D,Fuller RA

更新日期：2019-01-01 00:00:00

abstract：:In this Letter, 'released' should have been 'regulated' in the sentence starting: 'Deletion of Atg5 in the host similarly regulated circulating arginine and suppressed tumorigenesis...' This has been corrected online. ...

journal_title：Nature

authors： Poillet-Perez L,Xie X,Zhan L,Yang Y,Sharp DW,Hu ZS,Su X,Maganti A,Jiang C,Lu W,Zheng H,Bosenberg MW,Mehnert JM,Guo JY,Lattime E,Rabinowitz JD,White E

更新日期：2019-01-01 00:00:00

abstract：: ...

journal_title：Nature

authors： Wight AJ

更新日期：2019-01-01 00:00:00

abstract：: ...

journal_title：Nature

authors： Reyzin L

更新日期：2019-01-01 00:00:00

abstract：:Since the early 1980s, most electronics have relied on the use of complementary metal-oxide-semiconductor (CMOS) transistors. However, the principles of CMOS operation, involving a switchable semiconductor conductance controlled by an insulating gate, have remained largely unchanged, even as transistors are miniaturiz...

journal_title：Nature

authors： Manipatruni S,Nikonov DE,Lin CC,Gosavi TA,Liu H,Prasad B,Huang YL,Bonturim E,Ramesh R,Young IA

更新日期：2019-01-01 00:00:00

abstract：: ...

journal_title：Nature

authors： Silver A

更新日期：2019-01-01 00:00:00

abstract：:Ice sheets are currently ignored in global methane budgets1,2. Although ice sheets have been proposed to contain large reserves of methane that may contribute to a rise in atmospheric methane concentration if released during periods of rapid ice retreat3,4, no data exist on the current methane footprint of ice sheets....

journal_title：Nature

authors： Lamarche-Gagnon G,Wadham JL,Sherwood Lollar B,Arndt S,Fietzek P,Beaton AD,Tedstone AJ,Telling J,Bagshaw EA,Hawkings JR,Kohler TJ,Zarsky JD,Mowlem MC,Anesio AM,Stibal M

更新日期：2019-01-01 00:00:00

abstract：: ...

journal_title：Nature

authors： Nakar E

更新日期：2019-01-01 00:00:00

abstract：: ...

journal_title：Nature

authors：

更新日期：2019-01-01 00:00:00

abstract：:Endochondral ossification, an important process in vertebrate bone formation, is highly dependent on correct functioning of growth plate chondrocytes1. Proliferation of these cells determines longitudinal bone growth and the matrix deposited provides a scaffold for future bone formation. However, these two energy-depe...

journal_title：Nature

authors： Stegen S,Laperre K,Eelen G,Rinaldi G,Fraisl P,Torrekens S,Van Looveren R,Loopmans S,Bultynck G,Vinckier S,Meersman F,Maxwell PH,Rai J,Weis M,Eyre DR,Ghesquière B,Fendt SM,Carmeliet P,Carmeliet G

更新日期：2019-01-01 00:00:00

abstract：:Type-A γ-aminobutyric (GABAA) receptors are ligand-gated chloride channels with a very rich pharmacology. Some of their modulators, including benzodiazepines and general anaesthetics, are among the most successful drugs in clinical use and are common substances of abuse. Without reliable structural data, the mechanist...

journal_title：Nature

authors： Masiulis S,Desai R,Uchański T,Serna Martin I,Laverty D,Karia D,Malinauskas T,Zivanov J,Pardon E,Kotecha A,Steyaert J,Miller KW,Aricescu AR

更新日期：2019-01-01 00:00:00

abstract：: ...

journal_title：Nature

authors：

更新日期：2019-01-01 00:00:00

abstract：:Most patients with cancer either do not respond to immune checkpoint blockade or develop resistance to it, often because of acquired mutations that impair antigen presentation. Here we show that loss of function of the RNA-editing enzyme ADAR1 in tumour cells profoundly sensitizes tumours to immunotherapy and overcome...

journal_title：Nature

authors： Ishizuka JJ,Manguso RT,Cheruiyot CK,Bi K,Panda A,Iracheta-Vellve A,Miller BC,Du PP,Yates KB,Dubrot J,Buchumenski I,Comstock DE,Brown FD,Ayer A,Kohnle IC,Pope HW,Zimmer MD,Sen DR,Lane-Reticker SK,Robitschek EJ,Grif

更新日期：2019-01-01 00:00:00

abstract：:The Altai region of Siberia was inhabited for parts of the Pleistocene by at least two groups of archaic hominins-Denisovans and Neanderthals. Denisova Cave, uniquely, contains stratified deposits that preserve skeletal and genetic evidence of both hominins, artefacts made from stone and other materials, and a range o...

journal_title：Nature

authors： Jacobs Z,Li B,Shunkov MV,Kozlikin MB,Bolikhovskaya NS,Agadjanian AK,Uliyanov VA,Vasiliev SK,O'Gorman K,Derevianko AP,Roberts RG

更新日期：2019-01-01 00:00:00

abstract：: ...

journal_title：Nature

authors： Woolston C

更新日期：2019-01-01 00:00:00

abstract：: ...

journal_title：Nature

authors： Glausiusz J

更新日期：2019-01-01 00:00:00

abstract：:Laboratory measurements of sound velocities of high-pressure minerals provide crucial information on the composition and constitution of the deep mantle via comparisons with observed seismic velocities. Calcium silicate (CaSiO3) perovskite (CaPv) is a high-pressure phase that occurs at depths greater than about 560 ki...

journal_title：Nature

authors： Gréaux S,Irifune T,Higo Y,Tange Y,Arimoto T,Liu Z,Yamada A

更新日期：2019-01-01 00:00:00

abstract：:Change history: In Fig. 1c of this Letter, the two graphs were duplicates. The right panel of Fig. 1c has been corrected online. ...

journal_title：Nature

authors： Lai B,Gao W,Cui K,Xie W,Tang Q,Jin W,Hu G,Ni B,Zhao K

更新日期：2018-12-01 00:00:00

abstract：:Haematopoiesis is an essential process that evolved in multicellular animals. At the heart of this process are haematopoietic stem cells (HSCs), which are multipotent and self-renewing, and generate the entire repertoire of blood and immune cells throughout an animal's life1. Although there have been comprehensive stu...

journal_title：Nature

authors： Rosental B,Kowarsky M,Seita J,Corey DM,Ishizuka KJ,Palmeri KJ,Chen SY,Sinha R,Okamoto J,Mantalas G,Manni L,Raveh T,Clarke DN,Tsai JM,Newman AM,Neff NF,Nolan GP,Quake SR,Weissman IL,Voskoboynik A

更新日期：2018-12-01 00:00:00

abstract：:Observations of galaxies and primordial radiation suggest that the Universe is made mostly of non-luminous dark matter1,2. Several new types of fundamental particle have been proposed as candidates for dark matter3, such as weakly interacting massive particles (WIMPs)4,5. These particles would be expected to interact ...

journal_title：Nature

authors： COSINE-100 Collaboration.

更新日期：2018-12-01 00:00:00

abstract：: ...

journal_title：Nature

authors： Savage N

更新日期：2018-12-01 00:00:00

abstract：: ...

journal_title：Nature

authors： Hills R,Kulkarni G,Meerburg PD,Puchwein E

更新日期：2018-12-01 00:00:00

abstract：: ...

journal_title：Nature

authors： Davies J,Stoett P

更新日期：2018-12-01 00:00:00

abstract：: ...

journal_title：Nature

authors： Gewin V

更新日期：2018-12-01 00:00:00

abstract：: ...

journal_title：Nature

authors： Rios Rojas C

更新日期：2018-12-01 00:00:00

abstract：:The NLRP3 inflammasome, which has been linked to human inflammatory diseases, is activated by diverse stimuli. How these stimuli activate NLRP3 is unknown. Here we show that different NLRP3 stimuli lead to disassembly of the trans-Golgi network (TGN). NLRP3 is recruited to the dispersed TGN (dTGN) through ionic bondin...

journal_title：Nature

authors： Chen J,Chen ZJ

更新日期：2018-12-01 00:00:00

abstract：: ...

journal_title：Nature

authors： Ball P

更新日期：2018-12-01 00:00:00

abstract：: ...

journal_title：Nature

authors： Clayton EW

更新日期：2018-12-01 00:00:00

abstract：: ...

journal_title：Nature

authors： Mallapaty S

更新日期：2018-12-01 00:00:00

abstract：: ...

journal_title：Nature

authors：

更新日期：2018-12-01 00:00:00

abstract：:In Fig. 1b of this Article, a U was inadvertently inserted after G15 in the D loop. The original Article has not been corrected. ...

journal_title：Nature

authors： Naganuma M,Sekine SI,Chong YE,Guo M,Yang XL,Gamper H,Hou YM,Schimmel P,Yokoyama S

更新日期：2018-12-01 00:00:00

abstract：: ...

journal_title：Nature

authors：

更新日期：2018-12-01 00:00:00

abstract：: ...

journal_title：Nature

authors： Del Bello L

更新日期：2018-12-01 00:00:00

abstract：: ...

journal_title：Nature

authors： Goodman SN

更新日期：2018-12-01 00:00:00

abstract：: ...

journal_title：Nature

authors： Reardon S

更新日期：2018-12-01 00:00:00

abstract：: ...

journal_title：Nature

authors：

更新日期：2018-11-01 00:00:00

abstract：: ...

journal_title：Nature

authors： Witze A

更新日期：2018-11-01 00:00:00